In this work, we introduce three new datasets each collected for a specific purpose. The Vision-4-Vitals (V4V) dataset was curated for heart rate estimation and respiration rate estimation using an emotion elicitation protocol to introduce variations in physiological state under laboratory settings. We are currently collecting another large scale dataset with over 2000 subjects at India and Sierra Leone sites for multiple physiological signal estimation including blood pressure and oxygen saturation. Furthermore, we are also in the process of collecting a new dual-camera based blood pressure dataset with baseline measurement and modified blood pressure measurements through breathing activities. Finally, we introduce the continuous evaluation protocol and a new Transformer based approach that outperforms existing heart rate and respiration rate estimation methods.