Local quality assessment for optical coherence tomography - Robotics Institute Carnegie Mellon University

Local quality assessment for optical coherence tomography

Peter Barnum, Mei Chen, Hiroshi Ishikawa, Gadi Wollstein, and Joel Schuman
Conference Paper, Proceedings of International Symposium on Biomedical Imaging: From Nano to Macro (ISBI '08), pp. 392 - 395, May, 2008

Abstract

Optical Coherence Tomography (OCT) is a non-invasive tool for visualizing the retina. It is increasingly used to diagnose eye diseases such as glaucoma and diabetic maculopathy. However, diagnosis is only possible when the layers of the retina can be easily distinguished, which is when the images are evenly illuminated. Automated OCT quality assessment (i.e. signal strength) is only available for images as a whole. In this work, we present an automated method for local quality assessment. For training data, three OCT experts label the quality of each individual a-scan line in 270 OCT images. We extract features that are insensitive to pathology, and employ a hierarchy of support vector machines and histogram-based metrics. Our trained classifier is able to determine not only when signal strength is low, but also when it will affect doctorsÂ’ diagnostic ability. Our results improve over the state of the art in OCT quality assessment.

BibTeX

@conference{Barnum-2008-9969,
author = {Peter Barnum and Mei Chen and Hiroshi Ishikawa and Gadi Wollstein and Joel Schuman},
title = {Local quality assessment for optical coherence tomography},
booktitle = {Proceedings of International Symposium on Biomedical Imaging: From Nano to Macro (ISBI '08)},
year = {2008},
month = {May},
pages = {392 - 395},
}